What Is The Role Of Cannabinoid Receptors In Mood & Anxiety?

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Many people rely on cannabis to activate cannabinoid receptors in the brain and body. It does help elevate mood and relieve anxiety, but many people are curious if other ways are as effective. In this article, we’ll discuss what cannabinoid receptors are, how cannabinoid receptors ease anxiety, and how they improve mood. In the end, we’ll discuss how you can receive similar benefits by exploring Regen Labs Insta Zen.

RELATED: How To Improve Your Mental Focus 


What Are Cannabinoid Receptors?

The endocannabinoid system regulates different aspects of our health, including the immune and nervous systems. The system consists of two parts: endocannabinoids and cannabinoid receptors. Endocannabinoids are lipids that activate cannabinoid receptors CB1 and CB2.

Cannabinoid receptors are located in the brain and throughout the body. You may wonder, why do we have cannabinoid receptors? They are involved with decision-making, learning, memory, plus many of our behavioral and emotional reactions. Above all, they play a huge role in determining our mood and anxiety levels.


Cannabinoid Receptors Ease Anxiety

Cannabinoid receptors, in particular CB1, play a huge role in easing anxiety. Thus, anxiety and cannabinoids are linked together. Dr. Sachin Patel and his team at Vanderbilt University identified CB1 receptors in the amygdala. The amygdala is the brain’s core area for regulating emotional behavior, including our fight or flight response to stressful situations. Patel and his team discovered that the cannabinoid receptors like CB1 are blocked then anxiety increases. Patel later said, “Boosting this signaling system could represent a new treatment approach for these stress-linked disorders.”


Cannabinoids Receptors Improve Mood

Cannabinoid receptors may also improve due to the signaling of an endocannabinoid receptor called 2-arachidonoylglycerol (2-AG). 2-AG, also known as the “anxiety molecule,” plays a critical role in managing emotional behavior. Patel and his team showed that lower levels of 2-AG lead to more anxious and depressed moods. Similar to the CB1, Patel’s team found that by increasing and decreasing different amounts of 2-AG, you can augment mice’s stress responses. Higher amounts of 2-AG lead to the mice becoming more stress-resilient than before. This is the same mechanism that occurs when people consume cannabis to improve their mood.


Activate Cannabinoid Receptors with Insta Zen

Some people might be turned off by the idea of turning to cannabinoids for anxiety problems or unstable moods. Some might turn to benzodiazepines, but those have a whole list of side effects to keep in mind. Another option to try is Regen Labs Insta Zen.

Instead of relying on psychoactive drugs or prescribed medication, you can find peace thanks to a key ingredient in Insta Zen called DHH-B (dihydro honokiol-B). People have used DHH-B for centuries. It is approximately 2,000% stronger than honokiol, the magnolia bark extract from which it is derived. It not only boosts GABA (Gamma-Aminobutyric Acid), which creates a calming effect, but it also activates cannabinoid receptors. Since DHH-B can activate cannabinoid receptors, it helps reduce anxiety and elevate your mood.

Beyond DHH-B, Insta Zen includes other all-natural ingredients such as L-Theanine, Ashwagandha, Phosphatidylserine, and Valerian Root.



Cup with green tea and teapot on grey wooden background | What Is The Role Of Cannabinoid Receptors In Mood & Anxiety?

L-Theanine is a non-proteinaceous amino acid found in green tea. It contains neuroprotective, mood-enhancing, and relaxation properties. Alongside DHH-B, it can help reduce stress and anxiety in many different stressful situations.



Ashwagandha is an ancient medicinal herb that helps calm anxiety, specifically agoraphobia or fear of crowds in open spaces. It does this thanks to its ability to lower the stress hormone cortisol significantly.



Phosphatidylserine is a naturally occurring lipid that helps protect each cell in the body. It’s essential for cellular functioning, especially in the brain. Phosphatidylserine can help treat stress, depression, and ADHD.


Valerian Root

Valeriana officinalis plant in the meadow | What Is The Role Of Cannabinoid Receptors In Mood & Anxiety?

Valerian Root is an herb that is rich in valerenic acid, isovaleric acid, and other antioxidants. These are all associated with lowering anxiety and promoting healthy sleep. In addition, the amygdala responds to the valerian root and helps balance excessive thinking.

RELATED: List of Benzodiazepines Sides Effects + (Alternatives to Consider)


If you’re curious about elevating your mood and lowering your anxiety, check out Regen Labs Insta Zen. You don’t have to rely on cannabis or benzos; get your Zen back the natural way with proven ingredients of the highest quality.

It is a lot to think about! We get it. If you have questions about the role of cannabinoid receptors in mood and anxiety, Regen Labs has options for you. All Regen Labs products support the body’s natural systems for a healthy brain, skin, muscle, and sexual health.

Regen Labs products contain research-proven ingredients to boost the body’s natural ability to be healthy without toxins or synthetic chemicals.

Let’s talk! If you have questions, we would love to connect. Contact us at [email protected].


How have you learned about the role of cannabinoid receptors in mood and anxiety? Let us know your thoughts in the comment section below! 

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One Response

  1. I am taking an antidepressant but I am still having a lot of anxiety. Will I be able to take Insta Zen without having any interactions? Ultimately I would like to get off my antidepressant all together but have been unable to accomplish that thus far. Any suggestions would be greatly appreciated.

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